PrEP 2-1-1 dosing has not been studied with Descovy, and we do not recommend that people taking Descovy use 2-1-1 dosing at this time.īecause PrEP 2-1-1 is taken around times of sex instead of every day, PrEP 2-1-1 might make sense for people who have sex less frequently. PrEP 2-1-1 dosing is ONLY recommended for use with Truvada and generic Truvada (TDF/FTC). If you have sex more than 24 hours after taking your first dose (two pills), or over multiple days, you will need to continue taking one pill every day until you have taken two doses following the last time you have sex, at which point you can stop taking tablets. PrEP 2-1-1 is named for its schedule of dosing: You take two pills 2-24 hours before sex, one pill 24 hours after the initial dose, and one final pill 24 hours later.
Rather than taking Truvada once daily, PrEP 2-1-1 involves taking PrEP medication around times of sex instead of once per day.
